Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/10123
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dc.contributor.authorAdan Gökbulut, Aysun-
dc.contributor.authorBaran, Yusuf-
dc.date.accessioned2021-01-24T18:32:26Z-
dc.date.available2021-01-24T18:32:26Z-
dc.date.issued2014-
dc.identifier.issn0145-2126-
dc.identifier.urihttps://doi.org/10.1016/S0145-2126(14)70120-1-
dc.identifier.urihttps://hdl.handle.net/10123-
dc.description5th International Eurasian Hematology Congressen_US
dc.description.abstractIn Chronic Myeloid Leukemia (CML) treatment, despite therapeutic efficacy of tyrosine kinase inhibitors, resistance development and side effects cause problems. Fisetin, vitexin and hesperetin are plant-derived flavonoids. In this study, therapeutic potentials of fisetin, vitexin and hesperetin were determined in CML cells. Cytotoxic effects of flavonoids were determined by MTT assay while apoptotic effects were determined by changes in caspase- 3 activity, loss of mitochondrial membrane potential (MMP) and Annexin V/PI double staining. Cytostatic effects of the flavonoids were evaluated by propidium iodide staining using flow cytometry.en_US
dc.language.isoenen_US
dc.publisherElsevier Ltd.en_US
dc.relation.ispartofLeukemia Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleTherapeutic potential of fisetin, vitexin and hesperetin on chronic myeloid leukemia cellsen_US
dc.typeConference Objecten_US
dc.institutionauthorAdan Gökbulut, Aysun-
dc.institutionauthorBaran, Yusuf-
dc.departmentİzmir Institute of Technology. Molecular Biology and Geneticsen_US
dc.identifier.volume38en_US
dc.identifier.startpageS48en_US
dc.identifier.endpageS48en_US
dc.identifier.wosWOS:000347244200114en_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/S0145-2126(14)70120-1-
dc.relation.doi10.1016/S0145-2126(14)70120-1en_US
dc.coverage.doi10.1016/S0145-2126(14)70120-1en_US
dc.identifier.wosqualityQ3-
dc.identifier.scopusqualityQ2-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.openairetypeConference Object-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
item.cerifentitytypePublications-
crisitem.author.dept04.03. Department of Molecular Biology and Genetics-
crisitem.author.dept04.03. Department of Molecular Biology and Genetics-
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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