Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/10389
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dc.contributor.authorBilginer, Rumeysaen_US
dc.contributor.authorÖzkendir İnanç, Dilceen_US
dc.contributor.authorYıldız, Ümit Hakanen_US
dc.contributor.authorArslan Yıldız, Ahuen_US
dc.date.accessioned2021-01-24T18:34:28Z-
dc.date.available2021-01-24T18:34:28Z-
dc.date.issued2021-05en_US
dc.identifier.issn0021-8995-
dc.identifier.issn1097-4628-
dc.identifier.urihttps://doi.org/10.1002/app.50287-
dc.identifier.urihttps://hdl.handle.net/10389-
dc.description.abstractThe objective of this work is generation of propolis/polyvinyl alcohol (PVA) scaffold by electrospinning for 3D cell culture. Here, PVA used as co-spinning agent since propolis alone cannot be easily processed by electrospinning methodology. Propolis takes charge in maximizing biological aspect of scaffold to facilitate cell attachment and proliferation. Morphological analysis showed size of the electrospun nanofibers varied between 172-523 nm and 345-687 nm in diameter, for non-crosslinked and crosslinked scaffolds, respectively. Incorporation of propolis resulted in desired surface properties of hybrid matrix, where hybrid scaffolds highly favored protein adsorption. To examine cell compatibility, NIH-3T3 and HeLa cells were seeded on propolis/PVA hybrid scaffold. Results confirmed that integration of propolis supported cell adhesion and cell proliferation. Also, results indicated electrospun propolis/PVA hybrid scaffold provide suitable microenvironment for cell culturing. Therefore, developed hybrid scaffold could be considered as potential candidate for 3D cell culture and tissue engineering.en_US
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Inc.en_US
dc.relation.ispartofJournal of Applied Polymer Scienceen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject3D cell cultureen_US
dc.subjectBiomimeticen_US
dc.subjectElectrospinningen_US
dc.subjectPropolisen_US
dc.subjectTissue engineeringen_US
dc.titleBiocomposite scaffolds for 3D cell culture: Propolis enriched polyvinyl alcohol nanofibers favoring cell adhesionen_US
dc.typeArticleen_US
dc.authorid0000-0002-6922-4454en_US
dc.authorid0000-0003-0348-0575en_US
dc.departmentIzmir Institute of Technology. Biotechnology and Bioengineeringen_US
dc.departmentIzmir Institute of Technology. Photonicsen_US
dc.departmentIzmir Institute of Technology. Chemistryen_US
dc.identifier.wosWOS:000591768500001-
dc.identifier.scopusSCOPUS:2-s2.0-85096796889-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1002/app.50287-
dc.contributor.affiliationIzmir Institute of Technologyen_US
dc.contributor.affiliationIzmir Institute of Technologyen_US
dc.contributor.affiliationIzmir Institute of Technologyen_US
dc.contributor.affiliationIzmir Institute of Technologyen_US
dc.relation.doi10.1002/app.50287en_US
dc.coverage.doi10.1002/app.50287en_US
dc.description.volume138en_US
dc.description.issue17en_US
item.grantfulltextembargo_20240101-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.openairetypeArticle-
crisitem.author.deptDepartment of Chemistry-
crisitem.author.deptDepartment of Bioengineering-
Appears in Collections:Bioengineering / Biyomühendislik
Chemistry / Kimya
Photonics / Fotonik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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