Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/10777
Title: Three dimensional microfluidic device that determines metastatic capacity and homing choices
Authors: Pesen Okvur, Devrim
Izmir Institute of Technology
Keywords: Microfluidic device
Metastatic capacity
Homing choices
Issue Date: 2014
Publisher: European Patent Office
Abstract: The invention provides a device that mimics the in vivo tumor microenvironment comprising different cell types, matrices, biological molecules and chemicals. All steps of metastasis, namely, angiogenesis, matrix invasion, cell migration, intravasation, circulation, extravasation and new tumor formation, in addition to homing choices of cancer cells can simultaneously and jointly be investigated using the said microfluidic device. The design of the device with multiple adjacent channels comprising 3D cell-laden or cell free matrices(24, 25, 26, 27, 28, 29) neighboring a flow channel (30) allows determination of metastatic capacity and homing choices of cancer cells.
Description: Three dimensional microfluidic device that determines metastatic capacity and homing choices isimli buluşa ait, European Patent Office tarafından EP2741083A1 numarasıyla verilen patente ilişkin kayıttır.
URI: https://hdl.handle.net/11147/10777
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
Patent Koleksiyonu / Patent Collection

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