Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/11377
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dc.contributor.authorSözmen, Alper Baran-
dc.contributor.authorArslan Yıldız, Ahu-
dc.date.accessioned2021-11-06T09:47:01Z-
dc.date.available2021-11-06T09:47:01Z-
dc.date.issued2021-
dc.identifier.issn1613-4982-
dc.identifier.issn1613-4990-
dc.identifier.urihttps://doi.org/10.1007/s10404-021-02466-3-
dc.identifier.urihttps://hdl.handle.net/11147/11377-
dc.description.abstractMicrofluidic systems are relatively new technology field with a constant need of novel and practical manufacturing materials and methods. One of the main shortcomings of current methods is the inability to provide rapid bonding, with high bonding strength, and sound microchannel integrity. Herein we propose a novel method of assembly that overcomes the mentioned limitations. Polymer-assisted bonding is a novel, rapid, simple, and inexpensive method where a polymer is solubilized in a solvent and the constituted solution is used as a bonding agent. In this study, we combined this method with utilization of several phase-changing materials (PCMs) as channel-protective agents. Glauber's salt appeared to be more suitable as a channel-protective agent compared to rest of the salts that have been used in this study. Based on the bonding strength, quality analyses, leakage tests, and SEM imaging, the superior assisting bonding solvent was determined to be dichloromethane with a PMMA concentration of 2.5% (W/V). It showed a bonding strength of 23.794 MPa and a nearly non-visible bonding layer formation of 2.83 mu m in width which is proved by SEM imaging. The said combination of PCM, solvent, and polymer concentration also showed success in leakage tests and an application of micro-droplet generator fabrication. The application was carried out to test the applicability of developed prototyping methodology, which resulted in conclusive outcomes as the droplet generator simulation run in COMSOL Multiphysics version 5.1 software. In conclusion, the developed fabrication method promises simple, rapid, and strong bonding with sharp and clear micro-channel engraving.en_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofMicrofluidics and Nanofluidicsen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMicrofluidicsen_US
dc.subjectRapid prototypingen_US
dc.subjectMicrofabricationen_US
dc.subjectLaser ablationen_US
dc.subjectMicro-droplet generatoren_US
dc.titleCost-effective and rapid prototyping of PMMA microfluidic device via polymer-assisted bondingen_US
dc.typeArticleen_US
dc.authorid0000-0003-0348-0575-
dc.authorid0000-0002-2633-3837-
dc.institutionauthorSözmen, Alper Baran-
dc.departmentİzmir Institute of Technology. Bioengineeringen_US
dc.identifier.volume25en_US
dc.identifier.issue8en_US
dc.identifier.wosWOS:000669885700001en_US
dc.identifier.scopus2-s2.0-85109217636en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1007/s10404-021-02466-3-
dc.identifier.wosqualityQ2-
dc.identifier.scopusqualityQ2-
item.grantfulltextembargo_20250101-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.languageiso639-1en-
item.fulltextWith Fulltext-
crisitem.author.dept01. Izmir Institute of Technology-
crisitem.author.dept03.01. Department of Bioengineering-
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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