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Title: Size-based microparticle seperation using negative magnetophoresis
Authors: Solmaz Özçelik, Özge
Öksüz, Cemre
Tekin, Hüseyin Cumhur
Keywords: Microfluidic filtration
Negative magnetophoresis
Size-based separation
Issue Date: 2021
Publisher: Chemical and Biological Microsystems Society
Abstract: We present a new size-based microparticle separation device using negative magnetophoresis. Microparticles spiked in the paramagnetic medium were filtered with respect to their sizes in a microfluidic channel placed between two magnets. Negative magnetophoresis allows large microparticles to be captured before the magnets, while small microparticles pass through the magnets under a constant flow. With this method, we reached 84.2% capturing efficiency of large microparticles (44 µm diameter) and capturing purity of 80.3% in the presence of small microparticles (17 µm diameter) at 3 µL/min flow rate. The capturing purity could further improve up to 99% by increasing the flow rate.
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection

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