Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/12511
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dc.contributor.authorAldemir Dikici, Betülen_US
dc.contributor.authorDikici, Serkanen_US
dc.contributor.authorClaeyssens, Frederik-
dc.date.accessioned2022-10-03T13:55:31Z-
dc.date.available2022-10-03T13:55:31Z-
dc.date.issued2022-11-
dc.identifier.urihttps://doi.org/10.1016/j.reactfunctpolym.2022.105387-
dc.identifier.urihttps://hdl.handle.net/11147/12511-
dc.descriptionWe acknowledge the Engineering and Physical Sciences Research Council (Grant No. EP/I007695/1 ) and the Medical Research Council (Grant No. MR/L012669/1 ) for funding the equipment used in this study. The authors also acknowledge funding from the Department of Scientific Research Projects of Izmir Institute of Technology (IZTECH-BAP, 2021-IYTE-1-0110 ).en_US
dc.description.abstractEmulsion templating is an advantageous route for the fabrication of tissue engineering scaffolds. Emulsions are mostly stabilised using surfactants, and the performances of the surfactants depend on various parameters such as emulsification temperature and the presence of the electrolytes. In this study, we suggest that diluting solvent type also has a dramatic impact on the efficiency of the surfactant and morphology of the polymerised emulsions. For this, morphologies of polycaprolactone methacrylate-based polymerised emulsions, which are designed for tissue engineering applications and in vitro biocompatibilities, were shown by our group, prepared using four different surfactants, and three different solvents were investigated. Results showed that the diluting solvent used in the emulsion composition has a strong impact on the performance of the surfactant and consequently on the morphology of polymerised emulsions. Increasing surfactant concentration and diluting solvent volume have an opposite impact on the characteristics of emulsions. Scaffolds with average pore sizes changing from 10 to 78 μm could be fabricated. Establishing these relations enables us to have control over the overall morphology of polymerised emulsions and precisely engineer them for specific tissue engineering applications by tuning solvent and surfactant type and concentration.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofReactive and Functional Polymersen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiomaterialsen_US
dc.subjectEmulsion templatingen_US
dc.subjectPolyHIPEen_US
dc.subjectTissue engineeringen_US
dc.subjectPore sizeen_US
dc.titleSynergistic effect of type and concentration of surfactant and diluting solvent on the morphology of emulsion templated matrices developed as tissue engineering scaffoldsen_US
dc.typeArticleen_US
dc.authorid0000-0002-5516-469Xen_US
dc.authorid0000-0001-9933-5254en_US
dc.institutionauthorAldemir Dikici, Betülen_US
dc.institutionauthorDikici, Serkanen_US
dc.departmentİzmir Institute of Technology. Bioengineeringen_US
dc.identifier.wosWOS:000862639900004en_US
dc.identifier.scopus2-s2.0-85138117831en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.reactfunctpolym.2022.105387-
dc.relation.issn1381-5148en_US
dc.description.volume180en_US
local.message.claim2023-01-26T11:07:41.679+0300|||rp03855|||submit_approve|||dc_contributor_author|||None*
dc.identifier.scopusqualityQ1-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.languageiso639-1en-
item.fulltextWith Fulltext-
crisitem.author.dept03.01. Department of Bioengineering-
crisitem.author.dept03.01. Department of Bioengineering-
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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