Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/12561
Title: Development of novel nanotoxicity assessment method utilizing 3D printing system
Authors: Başlar, Muhammet Semih
Öksel Karakuş, Ceyda
Aldemir Dikici, Betül
Keywords: 3D cell culture
Toxicity
Nanomaterials
Issue Date: Sep-2022
Publisher: Elsevier
Abstract: Unique physicochemical properties of nanomaterials (NMs) make them a material of choice in various applications but also raise concerns about their potential toxicity. While the commercial use of nano-enabled materials is growing rapidly, their interaction with biological systems and environment are not yet fully understood [1, 2]. Traditionally, toxicity of nano-sized materials are assessed by 2D cell culture models due to their time and cost-related advantages but their simplicity often comes at the cost of accuracy. While these methods are considered as the first step in toxicological assessment of both nanosized and bulk-form materials, they fall short in mimicking the complexity of in vivo physiological environments.
URI: https://doi.org/10.1016/j.toxlet.2022.07.631
https://hdl.handle.net/11147/12561
Appears in Collections:Bioengineering / Biyomühendislik
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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