Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/12667
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dc.contributor.authorYıldırım, Özümtr
dc.contributor.authorArslan Yıldız, Ahutr
dc.date.accessioned2022-12-12T12:31:47Z-
dc.date.available2022-12-12T12:31:47Z-
dc.date.issued2022-11-
dc.identifier.urihttps://doi.org/10.1039/D2BM01184K-
dc.identifier.urihttps://hdl.handle.net/11147/12667-
dc.description.abstractA new generation of bio-inks that are soft, viscous enough, stable in cell culture, and printable at low printing pressures is required in the current state of 3D bioprinting technology. Hydrogels can meet these features and can mimic the microenvironment of soft tissues easily. Hydrocolloids are a group of hydrogels which have a suitable gelling capacity and rheological properties. According to the literature, polysaccharide-based hydrocolloids are used in the food industry, wound healing technologies, and tissue engineering. Quince seed hydrocolloids (QSHs), which consist of mostly glucuronoxylan, can easily be obtained from quince seeds by water extraction. In this study, the use of a QSH as a bio-ink was investigated. The suitability of QSH for the printing process was assessed by rheological, uniformity and pore factor analyses. Appropriate printing parameters were determined and the characterization of the bioprinted QSHs was performed by SEM analysis, water uptake capacity measurement, and protein adsorption assay. The bioprinted QSHs had excellent water uptake capacity and showed suitable protein adsorption behaviour. Analyses of the biocompatibility and cellular viability of bioprinted QSHs were conducted using NIH-3T3 fibroblast cells and the results were found to be high during short and long-term cell culture periods. It was proved that QSH is a highly promising bio-ink for 3D bioprinting and further tissue engineering applications.en_US
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.relation.ispartofBiomaterials Scienceen_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.subjectBioprintingen_US
dc.subjectHydrogelsen_US
dc.subjectQuince seed hydrocolloidsen_US
dc.titleDevelopment of a hydrocolloid bio-ink for 3D bioprintingen_US
dc.typeArticleen_US
dc.authorid0000-0001-7203-3870en_US
dc.authorid0000-0003-0348-0575en_US
dc.departmentİzmir Institute of Technology. Bioengineeringen_US
dc.identifier.wosWOS:000871604900001en_US
dc.identifier.scopus2-s2.0-85142918777en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr
dc.identifier.doi10.1039/d2bm01184k-
dc.identifier.pmid36278818-
dc.relation.issn2047-4849en_US
dc.description.volume10en_US
dc.description.issue23en_US
dc.description.startpage6707en_US
dc.description.endpage6717en_US
dc.identifier.scopusqualityQ1-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextembargo_20241101-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
crisitem.author.dept03.01. Department of Bioengineering-
Appears in Collections:Bioengineering / Biyomühendislik
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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