Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/14372
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBursali, Fatma-
dc.contributor.authorSahin, Yueksel-
dc.contributor.authorAygun, Muhittin-
dc.contributor.authorSevincek, Resul-
dc.contributor.authorBiyik, H. Halil-
dc.contributor.authorOzgener, Huseyin-
dc.contributor.authorGurbuz, Burcin-
dc.date.accessioned2024-05-05T14:57:05Z-
dc.date.available2024-05-05T14:57:05Z-
dc.date.issued2024-
dc.identifier.issn1387-7003-
dc.identifier.issn1879-0259-
dc.identifier.urihttps://doi.org/10.1016/j.inoche.2024.112268-
dc.identifier.urihttps://hdl.handle.net/11147/14372-
dc.description.abstractNovel control products are needed in the control of important insects like mosquitoes which are developing resistance to insecticides and larvicides currently in the market. Boron compounds have been demonstrated to exhibit antibacterial and anticancer effects. 1,2-diboranes with a long history and importance in boron chemistry have been described. These compounds are synthesized from reactions of 1,2-dichlordiborane derivatives with lidium amides (ArNHLi/Et2NLi, etc.). In addition to the three previously synthesized diborane compounds, five novel 1,2-diborane compounds were synthesized in good yield using the same method for the first time. The structures of the novel derivatives were characterized by nuclear magnetic resonance spectroscopy, and the molecular structure of one of them (2a) was also demonstrated using single crystal X-ray diffraction. In this preliminary study, the ovicidal and larvicidal effects of new 1,2-diamino-1,2-diborane derivatives against Aedes aegypti and Aedes albopictus eggs and larvae were investigated for the first time. Of these, 2a and 2e showed the highest ovicidal activity against both species, while 7, 4 and 2d showed particularly high larvicidal activity. Some 1,2-diborane derivatives were found to be significantly toxic, with LC50 values ranging from 14,930 to 27,975 mu g/mL. Some derivatives (6, 2a, 2c) were less effective against mosquito larvae. 1,2-Diborane derivatives have high ovicidal and larvicidal effects on mosquitoes and are therefore potential candidates for the development of new larvicides. Further studies are needed to evaluate its mode of action and safety. Understanding their mode of action against mosquito development is crucial to optimizing their use and reducing the potential development of resistance. Their potential effects on other mosquito species and non -target organisms need to be investigated.en_US
dc.description.sponsorshipAydin Adnan Menderes University BAP [FEF-22020, FEF-22015]en_US
dc.description.sponsorship<B>Acknowledgements</B> This study was supported by Aydin Adnan Menderes University BAP (project No: FEF-22020 and FEF-22015)en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiboraneen_US
dc.subjectOvicidalen_US
dc.subjectLarvicidal effectsen_US
dc.subjectAedes aegyptien_US
dc.subjectAedes albopictusen_US
dc.title1,2-Diboranes with strong donor substitutes: Synthesis, ovicidal and larvicidal effect on important vector speciesen_US
dc.typeArticleen_US
dc.departmentIzmir Institute of Technologyen_US
dc.identifier.volume162en_US
dc.identifier.wosWOS:001201890900001-
dc.identifier.scopus2-s2.0-85187404924-
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.inoche.2024.112268-
dc.authorscopusid57573677100-
dc.authorscopusid7005779304-
dc.authorscopusid56249121800-
dc.authorscopusid16445032300-
dc.authorscopusid8591432100-
dc.authorscopusid6603655255-
dc.authorscopusid6603655255-
dc.identifier.wosqualityQ1-
dc.identifier.scopusqualityQ2-
item.grantfulltextnone-
item.openairetypeArticle-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
Show simple item record



CORE Recommender

SCOPUSTM   
Citations

1
checked on Jul 19, 2024

WEB OF SCIENCETM
Citations

1
checked on Jul 20, 2024

Page view(s)

64
checked on Jul 22, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.