Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/2250
Title: Cobalt coated substrate for matrix-free analysis of small molecules by laser desorption/ionization mass spectrometry
Authors: Yalçın, Talat
Li, Liang
Keywords: X-ray diffraction
Cobalt-coated substrate
Desorption/ionization
Laser spectroscopy
Matrix-free target
Small molecule analysis
Issue Date: Dec-2009
Publisher: Elsevier Ltd.
Source: Yalçın, T. and Li, L. (2009). Cobalt coated substrate for matrix-free analysis of small molecules by laser desorption/ionization mass spectrometry. Applied Surface Science, 256(5), 1309-1312. doi:10.1016/j.apsusc.2009.10.030
Abstract: Small molecule analysis is one of the most challenging issues in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. We have developed a cobalt coated substrate as a target for matrix-free analysis of small molecules in laser desorption/ionization mass spectrometry. Cobalt coating of 60-70 nm thickness has been characterized by scanning electron microscopy, energy dispersive X-ray analysis, X-ray diffraction, and laser induced breakdown spectroscopy. This target facilitates hundreds of samples to be spotted and analyzed without mixing any matrices, in a very short time. This can save a lot of time and money and can be a very practical approach for the analysis of small molecules by laser desorption/ionization mass spectrometry.
URI: http://dx.doi.org/10.1016/j.apsusc.2009.10.030
http://hdl.handle.net/11147/2250
ISSN: 0169-4332
0169-4332
1873-5584
Appears in Collections:Chemistry / Kimya
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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