Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/2623
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dc.contributor.authorHacıoğlu, Elise-
dc.contributor.authorEsmer, Işıl-
dc.contributor.authorFomenko, Dmitri E.-
dc.contributor.authorGladyshev, Vadim N.-
dc.contributor.authorKoç, Ahmet-
dc.date.accessioned2016-12-14T12:07:10Z-
dc.date.available2016-12-14T12:07:10Z-
dc.date.issued2010-11-
dc.identifier.citationHacıoğlu, E., Esmer, I., Fomenko, D. E., Gladyshev, V. N., and Koç, A. (2010). The roles of thiol oxidoreductases in yeast replicative aging. Mechanisms of Ageing and Development, 131(11-12), 692-699. doi:10.1016/j.mad.2010.09.006en_US
dc.identifier.issn1872-6216-
dc.identifier.issn0047-6374-
dc.identifier.urihttp://doi.org/10.1016/j.mad.2010.09.006-
dc.identifier.urihttp://hdl.handle.net/11147/2623-
dc.description.abstractThiol-based redox reactions are involved in the regulation of a variety of biological functions, such as protection against oxidative stress, signal transduction and protein folding. Some proteins involved in redox regulation have been shown to modulate life span in organisms from yeast to mammals. To assess the role of thiol oxidoreductases in aging on a genome-wide scale, we analyzed the replicative life span of yeast cells lacking known and candidate thiol oxidoreductases. The data suggest the role of several pathways in controlling yeast replicative life span, including thioredoxin reduction, protein folding and degradation, peroxide reduction, PIP3 signaling, and ATP synthesis. © 2010 Elsevier Ireland Ltd.en_US
dc.description.sponsorshipDPT-2003K120690; TÜBA-GEBİP and NIH AG021518en_US
dc.language.isoenen_US
dc.publisherElsevier Ltd.en_US
dc.relation.ispartofMechanisms of Ageing and Developmenten_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectYeasten_US
dc.subjectOxidoreductaseen_US
dc.subjectOxidationen_US
dc.subjectLife spanen_US
dc.subjectAntioxidanten_US
dc.subjectAgingen_US
dc.titleThe roles of thiol oxidoreductases in yeast replicative agingen_US
dc.typeArticleen_US
dc.authoridTR115223en_US
dc.authoridTR110769en_US
dc.institutionauthorHacıoğlu, Elise-
dc.institutionauthorEsmer, Işıl-
dc.institutionauthorKoç, Ahmet-
dc.departmentİzmir Institute of Technology. Molecular Biology and Geneticsen_US
dc.identifier.volume131en_US
dc.identifier.issue11-12en_US
dc.identifier.startpage692en_US
dc.identifier.endpage699en_US
dc.identifier.wosWOS:000286555900005en_US
dc.identifier.scopus2-s2.0-78649909154en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.mad.2010.09.006-
dc.identifier.pmid20934449en_US
dc.relation.doi10.1016/j.mad.2010.09.006en_US
dc.coverage.doi10.1016/j.mad.2010.09.006en_US
dc.identifier.wosqualityQ1-
dc.identifier.scopusqualityQ1-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextopen-
crisitem.author.dept04.03. Department of Molecular Biology and Genetics-
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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