Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/2685
Title: Synthesis of stilbene-fused 2'-hydroxychalcones and flavanones
Authors: Akçok, İsmail
Çağır, Ali
Keywords: Chalcone
Flavanone
Heck reaction
Michael addition
Stilbene
Issue Date: Aug-2010
Publisher: Elsevier Ltd.
Source: Akçok, İ., and Çağır, A. (2010). Synthesis of stilbene-fused 2′-hydroxychalcones and flavanones. Bioorganic Chemistry, 38(4), 139-143. doi:10.1016/j.bioorg.2010.04.001
Abstract: Synthesis of stilbene-fused chalcones and flavanones were successfully completed. Molecules were designed in a way to mimic the structural features of both "stilbene and chalcones" or "stilbene and flavanones" at the same time, and synthesized by three steps. Heck reactions of 3-bromobenzaldehyde with styrene derivatives gave corresponding (E)-stilbenes, which were reacted with acetophenones to furnish stilbene-fused 2′-hydroxychalcones under basic conditions. Finally, intramolecular cyclization reactions were performed to produce stilbene-fused flavanones. © 2010 Elsevier Inc.
URI: http://doi.org/10.1016/j.bioorg.2010.04.001
http://hdl.handle.net/11147/2685
ISSN: 0045-2068
Appears in Collections:Chemistry / Kimya
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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