Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/2731
Title: Electrochemical investigation of biomolecular interactions between platinum derivatives and DNA by carbon nanotubes modified sensors
Authors: Yapaşan, Ece
Çalışkan, Ayfer
Karadeniz, Hakan
Erdem, Arzum
Keywords: Carbon nanotubes
Differential pulse voltammetry
DNA interactions
Oxaliplatin
Drug interactions
Issue Date: May-2010
Publisher: Elsevier Ltd.
Source: Yapasan, E., Çalışkan, A., Karadeniz, H., and Erdem, A. (2010). Electrochemical investigation of biomolecular interactions between platinum derivatives and DNA by carbon nanotubes modified sensors. Materials Science and Engineering B: Solid-State Materials for Advanced Technology, 169(1-3), 169-173. doi:10.1016/j.mseb.2009.10.024
Abstract: The biomolecular interactions of platinum derivatives widely used as anticancer drugs: cis-diamminedichloroplatinum(II) and oxaliplatin with calf thymus double-stranded DNA were studied using differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) in combination with single-walled carbon nanotubes modified graphite electrode (SWCNTs-GE) and unmodified graphite electrode (bare GE). The performance of these biomolecular interactions were explored at the electrode surface by monitoring the changes at guanine oxidation signal in terms of optimum interaction times by comparing the results of SWCNTs-GE with bare one. The features of these electrochemical sensors based on carbon nanotubes for monitoring of biomolecular interactions were discussed and compared with the earlier conventional ones. © 2009 Elsevier B.V. All rights reserved.
URI: http://doi.org/10.1016/j.mseb.2009.10.024
http://hdl.handle.net/11147/2731
ISSN: 0921-5107
0921-5107
1873-4944
Appears in Collections:Chemistry / Kimya
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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