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Title: A new robust nonlinear control algorithm for the regulation of blood glucose in diabetic patients
Authors: Özyetkin, Mine M.
Nath, Nitendra
Tatlıcıoğlu, Enver
Dawson, Darren M.
Keywords: Glucose
Robust control
Diabetic patient
Insulin concentrations
Pancreatic beta cells
Issue Date: 2012
Publisher: Institute of Electrical and Electronics Engineers Inc.
Source: Özyetkin, M. M., Nath, N., Tatlıcıoğlu, E., and Dawson, D. M. (2012, October 3-5). A new robust nonlinear control algorithm for the regulation of blood glucose in diabetic patients. Paper presented at the IEEE International Conference on Control Applications, CCA 2012. doi:10.1109/CCA.2012.6402670
Abstract: Diabetes mellitus is a growing health problem worldwide. Especially, the patients with Type 1 diabetes need strict glycemic control because they have deficiency of insulin production. Today, the aim of the researchers is to develop a fully automated closed loop control system (i. e., artificial pancreas which is capable of continuous glucose sensing and regulating) that replicates the function of pancreatic beta cells. This equipment is supposed to be capable of maintaining normal blood glucose level on a desired level (4-6.2 mmol/L) and taking all factors affecting glucose concentration into account without inducing hypoglycemia and hyperglycemia. In this paper, control of the Bergman minimal mathematical model to regulate blood glucose level is discussed. The control problem is complicated by the fact that the model is considered to be uncertain. Furthermore, only the glucose level is assumed to be available for control development and other states such as insulin concentration and plasma insulin concentration are assumed to be unavailable for measurement. A novel robust controller is proposed that guarantees practical tracking of a desired glucose concentration. © 2012 IEEE.
ISBN: 9781467345033
Appears in Collections:Electrical - Electronic Engineering / Elektrik - Elektronik Mühendisliği
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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