Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/5530
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dc.contributor.authorBozdağ, Gönensin Ozan-
dc.contributor.authorKaya, Alaattin-
dc.contributor.authorKoç, Ahmet-
dc.contributor.authorNoll, Gundula A.-
dc.contributor.authorPrüfer, Dirk-
dc.contributor.authorKarakaya, Hüseyin Çağlar-
dc.date.accessioned2017-05-17T06:52:41Z-
dc.date.available2017-05-17T06:52:41Z-
dc.date.issued2014-04-
dc.identifier.citationBozdağ, G.O., Kaya, A., Koç, A., Noll, G.A., Prüfer, D., and Karakaya, H.Ç. (2014). Characterization of a cDNA from Beta maritima that confers nickel tolerance in yeast. Gene, 538(2), 251-257. doi:10.1016/j.gene.2014.01.052en_US
dc.identifier.issn0378-1119-
dc.identifier.urihttps://doi.org/10.1016/j.gene.2014.01.052-
dc.identifier.urihttp://hdl.handle.net/11147/5530-
dc.description.abstractNickel is an essential micronutrient due to its involvement in many enzymatic reactions as a cofactor. However, excess of this element is toxic to biological systems. Here, we constructed a cDNA library from Beta maritima and screened it in the yeast system to identify genes that confer resistance to toxic levels of nickel. A cDNA clone (NIC6), which encodes for a putative membrane protein with unknown function, was found to help yeast cells to tolerate toxic levels of nickel. A GFP fused form of Nic6 protein was localized to multivesicular structures in tobacco epidermal cells. Thus, our results suggest a possible role of Nic6 in nickel and intracellular ion homeostasis.en_US
dc.description.sponsorshipIYTE-BAP; DPTen_US
dc.language.isoenen_US
dc.publisherElsevier Ltd.en_US
dc.relation.ispartofGeneen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBeta maritimaen_US
dc.subjectHeavy metal toxicityen_US
dc.subjectIon homeostasisen_US
dc.subjectNickelen_US
dc.subjectTransporter proteinen_US
dc.subjectYeasten_US
dc.titleCharacterization of a cDNA from Beta maritima that confers nickel tolerance in yeasten_US
dc.typeArticleen_US
dc.authoridTR24898
dc.institutionauthorBozdağ, Gönensin Ozan-
dc.institutionauthorKaya, Alaattin-
dc.institutionauthorKoç, Ahmet-
dc.institutionauthorKarakaya, Hüseyin Çağlar-
dc.departmentİzmir Institute of Technology. Molecular Biology and Geneticsen_US
dc.identifier.volume538en_US
dc.identifier.issue2en_US
dc.identifier.startpage251en_US
dc.identifier.endpage257en_US
dc.identifier.wosWOS:000333789000006en_US
dc.identifier.scopus2-s2.0-84893902129en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.gene.2014.01.052-
dc.identifier.pmid24487090en_US
dc.relation.doi10.1016/j.gene.2014.01.052en_US
dc.coverage.doi10.1016/j.gene.2014.01.052en_US
local.message.claim2022-06-06T11:53:20.650+0300|||rp00417|||submit_approve|||dc_contributor_author|||None*
dc.identifier.wosqualityQ3-
dc.identifier.scopusqualityQ1-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextopen-
crisitem.author.dept04.03. Department of Molecular Biology and Genetics-
crisitem.author.dept04.03. Department of Molecular Biology and Genetics-
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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