Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/5944
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dc.contributor.authorIşık, Tuğba-
dc.contributor.authorHorzum, Nesrin-
dc.contributor.authorYıldız, Ümit Hakan-
dc.contributor.authorLiedberg, Bo-
dc.contributor.authorDemir, Mustafa Muammer-
dc.date.accessioned2017-07-18T07:52:05Z
dc.date.available2017-07-18T07:52:05Z
dc.date.issued2016-07
dc.identifier.citationIsık, T., Horzum, N., Yıldız, Ü. H., Liedberg, B., and Demir, M. M. (2016). Utilization of electrospun polystyrene membranes as a preliminary step for rapid diagnosis. Macromolecular Materials and Engineering, 301(7), 827-835. doi:10.1002/mame.201600127en_US
dc.identifier.issn1438-7492
dc.identifier.issn1438-7492-
dc.identifier.issn1439-2054-
dc.identifier.urihttp://doi.org/10.1002/mame.201600127
dc.identifier.urihttp://hdl.handle.net/11147/5944
dc.description.abstractRecent advances in clinical practice drive deoxyribonucleic acid (DNA) as an important class of biomarker. Monitoring the change in their concentration suggests the initiation and/or progression of various disorders. However, low quantity of DNA biomarkers in body fluids requires a delicate isolation methodology that provides efficient separation and easy handling. This study describes a newer-generation separation technology relying on electrospun fibers of sub-micrometer diameter of a commodity polymer for DNA biomarkers in simulative serum. Fibrous polystyrene membranes are prepared by electrospinning and they are subjected to post-modification with Au. The composite membranes may provide a convenient environment for the removal of bovine serum albumin (BSA) from BSA and DNA mixtures. The eluent can be used as an efficient tool for detection of DNA biomarkers associated with diagnosis of numerous life-threatening diseases.en_US
dc.description.sponsorshipFABEDen_US
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Inc.en_US
dc.relation.ispartofMacromolecular Materials and Engineeringen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdsorptionen_US
dc.subjectBioseparationsen_US
dc.subjectDNA biomarkersen_US
dc.subjectElectrospinningen_US
dc.subjectBiomarkersen_US
dc.titleUtilization of electrospun polystyrene membranes as a preliminary step for rapid diagnosisen_US
dc.typeArticleen_US
dc.authoridTR197000en_US
dc.authoridTR147447en_US
dc.authoridTR130614en_US
dc.institutionauthorIşık, Tuğba-
dc.institutionauthorYıldız, Ümit Hakan-
dc.institutionauthorDemir, Mustafa Muammer-
dc.departmentİzmir Institute of Technology. Materials Science and Engineeringen_US
dc.identifier.volume301en_US
dc.identifier.issue7en_US
dc.identifier.startpage827en_US
dc.identifier.endpage835en_US
dc.identifier.wosWOS:000379939000006en_US
dc.identifier.scopus2-s2.0-84992312410en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1002/mame.201600127-
dc.relation.doi10.1002/mame.201600127en_US
dc.coverage.doi10.1002/mame.201600127en_US
dc.identifier.wosqualityQ2-
dc.identifier.scopusqualityQ1-
item.openairetypeArticle-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextopen-
crisitem.author.dept04.01. Department of Chemistry-
crisitem.author.dept03.09. Department of Materials Science and Engineering-
Appears in Collections:Chemistry / Kimya
Materials Science and Engineering / Malzeme Bilimi ve Mühendisliği
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Sürdürülebilir Yeşil Kampüs Koleksiyonu / Sustainable Green Campus Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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