Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/7809
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dc.contributor.authorBilginer, Rümeysa-
dc.contributor.authorArslan Yıldız, Ahu-
dc.date.accessioned2020-07-18T03:35:10Z-
dc.date.available2020-07-18T03:35:10Z-
dc.date.issued2020-
dc.identifier.issn0167-577X-
dc.identifier.urihttps://doi.org/10.1016/j.matlet.2020.128191-
dc.identifier.urihttps://hdl.handle.net/11147/7809-
dc.description.abstractThis study depicts easy process of propolis by co-electrospinning without using any toxic agent for biomedical applications. To achieve this, polyvinyl alcohol was utilized as co-spinning agent to fabricate biomimetic Propolis/PVA scaffold. Here, whilst PVA was used as a supportive material to accumulate propolis in scaffold, propolis was employed to enrich biologic aspect of scaffold. This strategy overcomes challenges of propolis processing originated from solubility problems and offers easy processability of propolis in order to use in biomedical applications. Electrospun Propolis/PVA scaffolds were crosslinked with glutaraldehyde and drop-cast model was utilized as a control. Formation of porous, bead-free nanofiber architectures was confirmed through surface morphology analysis, while drop-cast model shows non-porous morphology. Wettability results confirmed both crosslinking and integration of propolis into polyvinyl alcohol scaffold moved contact angle to hydrophobic region. Presence and amount of propolis in hybrid scaffolds were validated via absorbance spectrum results. Bioactivity and biocompatibility of propolis-enriched scaffolds were analyzed through protein adsorption capacity. Obtained findings are evidence that electrospinning methodology offers easy and biosafe process of propolis. Electrospun Propolis/PVA exhibits desired properties and could be potentially utilized as scaffold for tissue engineering or as a wound dressing graft in biomedical field. © 2020 Elsevier B.V.en_US
dc.language.isoenen_US
dc.publisherElsevier Ltd.en_US
dc.relation.ispartofMaterials Lettersen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiomimeticen_US
dc.subjectCo-electrospinningen_US
dc.subjectPolymeric compositesen_US
dc.subjectPropolisen_US
dc.subjectTissue engineeringen_US
dc.titleA facile method to fabricate propolis enriched biomimetic PVA architectures by co-electrospinningen_US
dc.typeArticleen_US
dc.institutionauthorBilginer, Rümeysa-
dc.institutionauthorArslan Yıldız, Ahu-
dc.departmentİzmir Institute of Technology. Bioengineeringen_US
dc.identifier.volume276en_US
dc.identifier.wosWOS:000554915000025en_US
dc.identifier.scopus2-s2.0-85086999112en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.doi10.1016/j.matlet.2020.128191-
dc.relation.doi10.1016/j.matlet.2020.128191en_US
dc.coverage.doi10.1016/j.matlet.2020.128191en_US
dc.identifier.wosqualityQ2-
dc.identifier.scopusqualityQ1-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
item.languageiso639-1en-
item.fulltextWith Fulltext-
crisitem.author.dept03.01. Department of Bioengineering-
Appears in Collections:Bioengineering / Biyomühendislik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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