Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/8859
Title: The effect of DOPA hydroxyl groups on wet adhesion to polystyrene surface: An experimental and theoretical study
Authors: Yıldız, Remziye
Özen, Sercan
Şahin, Hasan
Akdoğan, Yaşar
Keywords: Mussel adhesion
DOPA
Surface coverage
EPR spectroscopy
DFT calculations
Publisher: Elsevier
Abstract: Mussels wet adhesive performance has been arousing curiosity for a long time. It is found that 3,4-dihydroxyphenylalanine (DOPA) is responsible for adhesive properties of mussels. Despite a large body of research characterizing the interactions DOPA with hydrophilic surfaces, relatively few works have addressed the mechanism of interactions with hydrophobic surfaces. The benzene ring of DOPA is the main attributor to the adhesion on hydrophobic polystyrene (PS) surface. However, here we showed that two hydroxyl groups of catechol have also effects on wet adhesion. We studied wet adhesive properties of DOPA, tyrosine and phenylalanine functionalized PEG polymers, PEG-(N-Boc-L-DOPA)(4), PEG-(N-Boc-L-Tyrosine)(4), PEG-(N-Boc-L-Phenylalanine)(4), on spin labeled PS nanobeads (SL-PS) by electron paramagnetic resonance (EPR) spectroscopy. Surface coverage ratio of SL-PS upon additions of PEG-(N-Boc-L-DOPA)(4), PEG-(N-Boc-L-Tyrosine)(4) and PEG-(N-Boc-L-Phenylalanine)(4) showed that SL-PS was covered with 70%, 50% and 0%, respectively. This showed that spontaneous wet adhesion on PS increases with the number of amino acids hydroxyl groups. This is also supported with the density functional theory (DFT) energy calculations and ab-initio molecular dynamics (AIMD) simulations. In water, interactions between water molecules and hydroxyl groups on the catechol induce catechol adhesion via 7C-7C stacking between the catechol and double styrene rings which were already tilted out with water.
URI: https://doi.org/10.1016/j.matchemphys.2019.122606
https://hdl.handle.net/11147/8859
ISSN: 0254-0584
1879-3312
Appears in Collections:Materials Science and Engineering / Malzeme Bilimi ve Mühendisliği
Photonics / Fotonik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Files in This Item:
File SizeFormat 
1-s2.0-S0254058419314166-main.pdf2.06 MBAdobe PDFView/Open
Show full item record



CORE Recommender

SCOPUSTM   
Citations

9
checked on Nov 29, 2024

WEB OF SCIENCETM
Citations

7
checked on Nov 16, 2024

Page view(s)

3,174
checked on Nov 25, 2024

Download(s)

504
checked on Nov 25, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.