Please use this identifier to cite or link to this item: https://hdl.handle.net/11147/9348
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dc.contributor.authorUddin, Fayyaz-
dc.contributor.authorKhan, Nasar-
dc.contributor.authorGhani, Shamsul-
dc.contributor.authorKhan, Saeed A.-
dc.date.accessioned2020-07-25T22:10:39Z-
dc.date.available2020-07-25T22:10:39Z-
dc.date.issued2016-
dc.identifier.issn0326-2383-
dc.identifier.issn2362-3853-
dc.identifier.urihttps://hdl.handle.net/11147/9348-
dc.description.abstractPolypharmacy in tuberculosis is used to prevent occurrence of resistance to mycobacteria. However, drug-drug interaction is one of the undesirable consequences of polypharmacy, that may lead to ineffective medication or change in therapeutic response. The objective of the study was to identify prevalence, types and nature of potential drug-drug interactions in tuberculosis patients at Khyber Teaching Hospital, Peshawar Pakistan. Medical records of 409 randomly-selected patients were reviewed for pDDIs using Micromedex Database. Results show that total 304 interacting-combinations lead to 1437 potential drug-drug interactions. 87.5% of the these potential drug-drug interactions were of moderate and major severity (i.e., 65.6% and 44.3% respectively). With regards to scientific-evidence, almost 50% of the potential drug-drug interactions were good documented while 34.7% had fair level of documentation. Furthermore, we have listed some of the interacting drug combinations, particularly most frequent major and moderate interactions, will help health care professionals to review their established therapeutic strategy for tuberculosis patients in their clinical settings.en_US
dc.language.isoenen_US
dc.publisherColegio de Farmaceuticos de la Provincia de Buenos Airesen_US
dc.relation.ispartofLatin American Journal of Pharmacyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDrug interactionsen_US
dc.subjectPolypharmacyen_US
dc.subjectTuberculosisen_US
dc.titleFrequency and levels of potential drug-drug interactions in tuberculosis patients of a teaching hospital in Pakistanen_US
dc.typeArticleen_US
dc.institutionauthorKhan, Nasar-
dc.departmentİzmir Institute of Technology. Molecular Biology and Geneticsen_US
dc.identifier.volume35en_US
dc.identifier.issue5en_US
dc.identifier.startpage1051en_US
dc.identifier.endpage1055en_US
dc.identifier.wosWOS:000381938000031en_US
dc.identifier.scopus2-s2.0-84964813391en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.identifier.wosqualityQ4-
dc.identifier.scopusqualityQ3-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.fulltextWith Fulltext-
item.openairetypeArticle-
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection
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