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Title: Semi-synthetic studies on astragaloside VII and immunomodulatory activities of the derivatives
Authors: Yakuboğulları, Nilgün
Sağ, Duygu
Çağır, Ali
Bedir, Erdal
Issue Date: 2019
Publisher: Georg Thieme Verlag
Abstract: Adjuvants have been used in vaccine sector since 1920s to increase the immunogenicity of antigens, reduce the dosage and minimize frequency of immunizations [1]. The use of saponins as adjuvant in the prophylactic/therapeutic human and veterinary vaccines, and investigation of their immunomodulatory activities have gained importance in recent years [2],[3]. Astragaloside VII (AST VII), a triterpenoid saponin isolated from Astragalus species, stimulates Th1 mediated immune response, antigen-specific antibody response and splenocyte proliferation.
Description: 67th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research (GA) -- SEP 01-05, 2019 -- Innsbruck, AUSTRIA
ISSN: 0032-0943
Appears in Collections:Bioengineering / Biyomühendislik
Chemistry / Kimya
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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