Üçüncü, MuhammedCantürk, CerenKarakuş, ErmanZeybek, HüseyinBozkaya, UğurSoydaş, EmineŞahin, ErtanEmrullahoğlu, Mustafa2017-06-282017-06-282016Üçüncü, M. Cantürk, C., Karakuş, E., Zeybek, H., Bozkaya, U., Soydaş, E., Şahin, E., and Emrullahoğlu, M. (2016). A rare γ-pyranopyrazole skeleton: Design, one-pot synthesis and computational study. Organic and Biomolecular Chemistry, 14/31), 7490-7494. doi:10.1039/c6ob01099g1477-05201477-0539http://doi.org/10.1039/c6ob01099ghttps://hdl.handle.net/11147/5796Drawing upon a consecutive amide coupling and intramolecular cyclisation pathway, a one-pot, straightforward synthetic route has been developed for a range of pyrazole fused γ-pyrone derivatives. The reaction mechanism proposed for the chemoselective formation of γ-pyranopyrazole is furthermore fully supported by experimental and computational studies. © The Royal Society of Chemistry 2016.eninfo:eu-repo/semantics/openAccessPositive ionsPyrazolesAmide couplingsReaction mechanismArticle2-s2.0-8498123756910.1039/c6ob01099g