Şahin, YükselÖzgener, HüseyinPoyrazoğlu Çoban, EsinSevinçek, ResulBıyık, Halil H.Özgener, HüseyinAygün, Muhittin04.01. Department of Chemistry04. Faculty of Science01. Izmir Institute of Technology2021-01-242021-01-2420210045-20681090-2120https://doi.org/10.1016/j.bioorg.2020.104494https://hdl.handle.net/11147/102331,2-diborolanes with strong and without strong donor substituents have been described, and are also referred to as 1,2-diboracyclopentane. The 1,2-diaryl/alkyl-amino-1,2-diboracyclopentanes 2, 3, and 4 were obtained in good yield after the reaction of 1,2-dichloro-1,2-diboracyclopentane 1 with ArNHLi and Me3Si-NR2. The structures of these new derivatives were characterized by nuclear magnetic resonance spectroscopy. The molecular structures of 2b, 2c, 2e, 4, and 5f were also determined by single-crystal X-ray diffraction. The newly synthesized 1,2-borolanes are stable in air and showed particularly high activity against some Gram-positive bacteria. © 2020 Elsevier Inc.eninfo:eu-repo/semantics/closedAccessAntimicrobialDiboracyclopentaneDiborolaneHeterocyclesArticle2-s2.0-8509703885310.1016/j.bioorg.2020.104494