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Title: Advantage of co-culture strategy for targeted cancer treatment and in vitro studies
Authors: Ulu, Gizem Tuğçe
Bayram, Nazende Nur
Dinçer İşoğlu, Sevil
Baran, Yusuf
Keywords: Breast cancer
Issue Date: 2021
Publisher: Elsevier
Abstract: Breast cancer tissues include carcinoma cells and stromal cells, and intra-tumoral stroma that consists of different types of cells. For this point, cell-cell interaction and communication have a potential role in cancer progression. Mono-cell culture is used for cancer treatment approaches. However, cell-cell interaction and communication can not be evaluated on mono-culture cells. So, co-culture models provide low-cost screening to determine cell proliferation for drug application before moving forward to in vivo models. Also, determination of cell morphology in co culture system is critical to understand advantages.
ISSN: 0923-7534
Appears in Collections:Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

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